C Met Antibody Cell Signaling

Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3.

C met antibody cell signaling. Zero bias scores article reviews protocol conditions and more. C met also called tyrosine protein kinase met or hepatocyte growth factor receptor hgfr is a protein that in humans is encoded by the met gene the protein possesses tyrosine kinase activity. 99 100 based on 5 pubmed citations. Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3.

Anti c met supplied by cell signaling technology inc used in various techniques. Met is a tyrosine kinase receptor for the hepatocyte growth factor. These fundamental events are important for all of the biological functions involving met kinase activity. Yin l et al.

These fundamental events are important for all of the biological functions involving met kinase activity. The primary single chain precursor protein is post translationally cleaved to produce the alpha and beta subunits which are disulfide linked to form the mature receptor. Red loading control ab18058 observed at 130 kda. Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3.

Microrna 200a suppresses migration and invasion and enhances the radiosensitivity of nsclc cells by inhibiting the hgf c met signaling pathway. Du m et al. Wild type hap1 whole cell lysate lane 2. Oncol rep 41 1497 1508 2019.

Anti met c met antibody epr19067 ab216574 at 1 1000 dilution lane 1. It is linked to functions such as cell proliferation scattering morphogenesis and survival. These fundamental events are important for all of the biological functions involving met kinase activity. In order to learn how oncogene addiction can be broken in tumors with met amplification by the anti c met monoclonal antibody abt 700 cell signaling technology c met antibody cell signaling 3077 was used in immunohistochemistry paraffin section on human samples fig 3 and in western blot on human samples fig 1.

Microrna 365a 3p inhibits c rel mediated nf b signaling and the progression of pancreatic cancer. Merged signal red and green. Green ab216574 observed at 155 kda. Ligand binding at the cell surface induces autophosphorylation of met that provides docking sites for downstream signaling molecules.

Ab74217 has been referenced in 9 publications.